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Rat Anti-Mouse CD45RC-BIOT (GL24)
Cat. No.:
1685-08
Biotin Anti-Mouse CD45RC antibody for use in flow cytometry and immunoprecipitation assays.
$308.00
| Clone | GL24 |
|---|---|
| Isotype | Rat (Lewis) IgMκ |
| Isotype Control | Rat IgM-BIOT (NIP/M-2) |
| Specificity | Mouse CD45RC |
| Description | CD45RC represents an exon C-dependent isoform of CD45 glycoprotein. It is expressed at high density on all B lymphocytes, at intermediate density on most CD8+ splenic T cells, and on two subpopulations of CD4+ splenic T cells with high and low density of expression. CD45RC is also present on a small subset of thymocytes. |
| Immunogen | Activated DBA/2 B cells |
| Conjugate | BIOT (Biotin) |
| Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C |
| Applications | Flow Cytometry – Quality tested 1-3 Immunoprecipitation – Reported in literature 1 |
| RRID Number | AB_2795139 |
| Gene ID | 19264 (Mouse) |
| Gene ID Symbol | Ptprc (Mouse) |
| Gene ID Aliases | loc; B220; Cd45; L-CA; Ly-5; T200; CD45R; Lyt-4 |
| UniProt ID | P06800 (Mouse |
| UniProt Name | PTPRC_MOUSE (Mouse) |
Documentation
Certificate of Analysis Lookup
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- 1. Hathcock KS, Laszlo G, Dickler HB, Sharrow SO, Johnson P, Trowbridge IS, et al. Expression of variable exon A-, B-, and C-specific CD45 determinants on peripheral and thymic T cell populations. J Immunol. 1992;148:19-28. (Immunogen, IP, FC)
- 2. Hathcock KS, Hirano H, Murakami S, Hodes RJ. CD45 expression by B cells. Expression of different CD45 isoforms by subpopulations of activated B cells. J Immunol. 1992;149:2286-94. (FC)
- 3. Czömpöly T, Lábadi A, Balázs M, Németh P, Balogh P. Use of cyclic peptide phage display library for the identification of a CD45RC epitope expressed on murine B cells and their precursors. Biochem Biophys Res Commun. 2003;307:791-6. (FC)
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