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Rat Anti-Mouse IL-17A-UNLB (TC11-8H4)
Cat. No.:
10214-01
Purified Anti-Mouse IL-17A antibody for use in flow cytometry, ELISA, and ELISpot assays.
$281.00
| Clone | TC11-8H4 |
|---|---|
| Isotype | Rat IgG1κ |
| Isotype Control | Rat IgG1-UNLB (KLH/G1-2-2) |
| Specificity | Mouse IL-17A |
| Alternative Names | Interleukin-17A, cytotoxic T lymphocyte-associated antigen 8, CTLA-8 |
| Immunogen | E. coli-expressed mouse IL-17 |
| Conjugate | UNLB (Unconjugated) |
| Buffer Formulation | Borate buffered saline, pH 8.2 |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C |
| Applications | ELISA-Detection – Quality tested 1 Flow Cytometry – Quality tested 5 ELISpot-Capture – Reported in literature 2 ELISpot-Detection – Reported in literature 3,4 Note – May be paired with the purified clone TC11-18H10 (SB Cat. No. 10215-01) in a sandwich ELISA |
| RRID Number | AB_2794256 |
| Gene ID | 16171 (Mouse) |
| Gene ID Symbol | Il17a (Mouse) |
| Gene ID Aliases | Ctla-8; Ctla8; IL-17; IL-17A; Il17 |
| UniProt ID | Q62386 (Mouse |
| UniProt Name | IL17_MOUSE (Mouse) |
Documentation
Certificate of Analysis Lookup
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- 1. Amsen D, de Visser KE, Town T. Approaches to determine expression of inflammatory cytokines. Methods Mol Biol. 2009;511:107-42. (ELISA-Detection)
- 2. Kish DD, Li X, Fairchild RL. CD8 T cells producing IL-17 and IFN-γ initiate the innate immune response required for responses to antigen skin challenge. J Immunol. 2009;182:5949-59. (ELISPOT-Capture)
- 3. Faust SM, Lu G, Marini BL, Zou W, Gordon D, Iwakura Y, et al. Role of T cell TGFβ signaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection. J Immunol. 2009;183:7297-306. (ELISPOT-Detection)
- 4. Nekrasova T, Shive C, Gao Y, Kawamura K, Guardia R, Landreth G, et al. ERK1-deficient mice show normal T cell effector function and are highly susceptible to experimental autoimmune encephalomyelitis. J Immunol. 2005;175:2374-80. (ELISPOT-Detection)
- 5. Bending D, Newland S, Krejcí A, Phillips JM, Bray S, Cooke A. Epigenetic changes at Il12rb2 and Tbx21 in relation to plasticity behavior of Th17 cells. J Immunol. 2011;186:3373-82. (FC)
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