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Clone | I3/2.3 |
---|---|
Isotype | Rat (Lewis) IgG2bλ |
Isotype Control | Rat IgG2b-AF488 (KLH/G2b-1-2) |
Specificity | Mouse CD45 |
Alternative Names | LCA, leukocyte common antigen, T200, Ly-5, Receptor-type tyrosine-protein phosphatase C, Lyt-4, Ptprc |
Description | CD45 is the common leukocyte antigen and is expressed on all cells of hematopoietic origin except erythrocytes. CD45 exists as a number of different isoforms which result from alternative RNA splicing of exons 4, 5 and 6. The I3/2.3 monoclonal antibody recognizes a framework epitope present on all CD45 isoforms. The CD45 molecule has been implicated as playing a key role in thymic development and in antigen-driven proliferation of T cells. |
Immunogen | T1M1 (Thy-1─c) cells |
Conjugate | AF488 (Alexa Fluor® 488) |
Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide |
Clonality | Monoclonal |
Concentration | 0.5 mg/mL |
Volume | 0.2 mL |
Recommended Storage | 2-8°C; Avoid exposure to light |
Trademark Information | Alexa Fluor® is a registered trademark of Thermo Fisher Scientific, Inc. or its subsidiaries |
Applications |
Flow Cytometry – Quality tested 2,5-7 Immunohistochemistry-Frozen Sections – Reported in literature 3,4 Immunoprecipitation – Reported in literature 1,2 |
RRID Number | AB_2795110 |
Gene ID |
19264 (Mouse) |
Gene ID Symbol |
Ptprc (Mouse) |
Gene ID Aliases | loc; B220; Cd45; L-CA; Ly-5; T200; CD45R; Lyt-4 |
UniProt ID |
P06800 (Mouse |
UniProt Name |
PTPRC_MOUSE (Mouse) |
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