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Rat Anti-Mouse CD24-LE/AF (91)
Cat. No.:
1590-14
Low Endotoxin/Azide Free Anti-Mouse CD24 antibody for use in flow cytometry and immunohistochemistry assays.
$270.00
| Clone | 91 |
|---|---|
| Isotype | Rat IgG2aκ |
| Isotype Control | Rat IgG2a-LE/AF (KLH/G2a-1-1) |
| Specificity | Mouse CD24 |
| Alternative Names | Heat stable antigen, HSA |
| Description | CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P-selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. |
| Conjugate | LE/AF (Low Endotoxin/Azide Free) |
| Buffer Formulation | Phosphate buffered saline, pH 7.4 |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C; Handle under aseptic conditions |
| Applications | Flow Cytometry – Quality tested 2 Immunohistochemistry-Frozen Sections – Reported in literature 1 |
| RRID Number | AB_2794996 |
| Gene ID | 12484 (Mouse) |
| Gene ID Symbol | Cd24a (Mouse) |
| Gene ID Aliases | HSA; Cd24; Ly-52; nectadrin |
| UniProt ID | P24807 (Mouse |
| UniProt Name | CD24_MOUSE (Mouse) |
Documentation
Certificate of Analysis Lookup
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- 1. Frings PW, Van Elssen CH, Wieten L, Matos C, Hupperets PS, Schouten HC, et al. Elimination of the chemotherapy resistant subpopulation of 4T1 mouse breast cancer by haploidentical NK cells cures the vast majority of mice. Breast Cancer Res Treat. 2011;130:773-81. (IHC-FS)
- 2. Zhou X, Bailey-Bucktrout S, Jeker LT, Penaranda C, Martinez-Llordella M, Ashby M, et al. Foxp3 instability leads to the generation of pathogenic memory T cells in vivo. Nat Immunol. 2009;10:1000-7. (FC)
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