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Rat Anti-Mouse BP-1-BIOT (FG35.4)
Cat. No.:
1770-08
Biotin Anti-Mouse BP-1 antibody for use in flow cytometry assays.
$248.00
| Clone | FG35.4 |
|---|---|
| Isotype | Rat IgG1κ |
| Isotype Control | Rat IgG1-BIOT (KLH/G1-2-2) |
| Specificity | Mouse BP-1 |
| Alternative Names | Ly-51, 6C3, aminopeptidase A, glutamyl aminopeptidase |
| Description | BP-1, also known as Ly-51 and 6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa. Originally identified on the surface of pre-B cell lymphomas the cDNA encoding BP-1 has been cloned and found to represent aminopeptidase A. It is expressed at high levels on bone marrow stromal cell lines which support in vitro B lymphopoiesis and on a wide variety of mouse tissues known to possess aminopeptidase activity. Subsets of normal bone marrow pre-B and B cells express low levels of BP-1 which is rapidly upregulated on pre-B cells in the presence of IL-7. The BP-1 marker is commonly used to identify B cells in different stages of development. |
| Conjugate | BIOT (Biotin) |
| Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C |
| Applications | Flow Cytometry – Quality tested 1 |
| RRID Number | AB_2795265 |
| Gene ID | 13809 (Mouse) |
| Gene ID Symbol | Enpep (Mouse) |
| Gene ID Aliases | APA; Ly51; Ly-51; Bp-1/6C3; 6030431M22Rik |
| UniProt ID | P16406 (Mouse |
| UniProt Name | AMPE_MOUSE (Mouse) |
Documentation
Certificate of Analysis Lookup
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- 1. Welner R, Swett DJ, Pelsue SC. Age-related loss of bone marrow pre-B- and immature B-lymphocytes in the autoimmune-prone flaky skin mutant mice. Autoimmunity. 2005;38:399-408. (FC)
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