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Rat Anti-Human IL-6-BIOT (MQ2-39C3)
Cat. No.:
10121-08
Biotin Anti-Human IL-6 antibody for use in ELISA, ELISpot, and multiplex assays.
$253.00
| Clone | MQ2-39C3 |
|---|---|
| Isotype | Rat IgG2aκ |
| Isotype Control | Rat IgG2a-BIOT (KLH/G2a-1-1) |
| Specificity | Human/Rhesus/Cynomolgus IL-6 |
| Alternative Names | Interleukin-6, hepatocyte stimulating factor, HSF, hepatocyte growth factor, HGF, B cell stimulating factor-2, BSF-2, BSF2, cytotoxic T cell differentiation factor, CDF, hybridoma/plasmacytoma growth factor, HPGF |
| Immunogen | COS-expressed human IL-6 |
| Conjugate | BIOT (Biotin) |
| Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C |
| Applications |
ELISA-Detection – Quality tested 3,4 ELISA-Capture – Reported in literature 1,2 ELISpot-Detection – Reported in literature 3,5 Neutralization – Reported in literature 1 Multiplex-Detection – Reported in literature 6 Note – May be paired with the purified clone MQ2-13A5 (SB Cat. No. 10120-01) in a sandwich ELISA |
| RRID Number | AB_2794167 |
| Gene ID |
3569 (Human) 705819 (Rhesus) 102138971 (Cynomolgus) |
| Gene ID Symbol |
IL6 (Human) IL6 (Rhesus) IL6 (Cynomolgus) |
| Gene ID Aliases | BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6; EGK_13861 |
| UniProt ID |
P05231 (Human P51494 (Rhesus P79341 (Cynomolgus |
| UniProt Name |
IL6_HUMAN (Human) IL6_MACMU (Rhesus) IL6_MACFA (Cynomolgus) |
Documentation
Certificate of Analysis Lookup
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- 1. Abrams JS, Roncarolo M, Yssel H, Andersson U, Gleich GJ, Silver JE. Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol Rev. 1992;127:5-24. (ELISA-Capture, Neut)
- 2. Abrams JS. Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies. Curr Protoc Immunol. 2001;6.20:1-15. (ELISA-Capture)
- 3. Mäkitalo B, Andersson M, Areström I, Karlén K, Villinger F, Ansari A, et al. ELISpot and ELISA analysis of spontaneous, mitogen-induced and antigen-specific cytokine production in cynomolgus and rhesus macaques. J Immunol Methods. 2002;270:85-97. (ELISA-Detection, ELISPOT-Detection, Rhesus & Cynomolgus Reactivity)
- 4. Zhao W, Oskeritzian CA, Pozez AL, Schwartz LB. Cytokine production by skin-derived mast cells: endogenous proteases are responsible for degradation of cytokines. J Immunol. 2005;175:2635-42. (ELISA-Detection)
- 5. Hansson T, Dannæus A, Klareskog L. Cytokine-producing cells in peripheral blood of children with coeliac disease secrete cytokines with a type 1 profile. Clin Exp Immunol. 1999;116:246-50. (ELISPOT-Detection)
- 6. Hutchinson KL, Villinger F, Miranda ME, Ksiazek TG, Peters CJ, Rollin PE. Multiplex analysis of cytokines in the blood of cynomolgus macaques naturally infected with Ebola virus (Reston serotype). J Med Virol. 2001;65:561-6. (Multiplex-Detection, Cynomolgus Reactivity)
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