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Clone | PK136 |
---|---|
Isotype | Mouse (C3H x BALB/c) IgG2aκ |
Isotype Control | Mouse IgG2a-PACBLU (HOPC-1) |
Specificity | Mouse NK1.1 |
Alternative Names | Ly-55, CD161b/CD161c |
Description | NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL/6, NZB, and CE). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice. |
Immunogen | CE mouse spleen enriched for NK-1+ cells and bone marrow cells |
Conjugate | PACBLU (Pacific Blueâ„¢) |
Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide |
Clonality | Monoclonal |
Concentration | 0.5 mg/mL |
Volume | 0.2 mL |
Recommended Storage | 2-8°C; Avoid exposure to light |
Trademark Information | Pacific Blueâ„¢ is a trademark of Thermo Fisher Scientific, Inc. or its subsidiaries |
Applications |
Flow Cytometry – Quality tested 1,3-5,8,9 Immunohistochemistry –Reported in literature 8 Immunoprecipitation – Reported in literature 3,4 Depletion – Reported in literature 2,7 Complement Mediated Cell Depletion – Reported in literature 5 Blocking – Reported in literature 4 Activation – Reported in literature 6 |
RRID Number | AB_2795352 |
Gene ID |
17059 (Mouse) |
Gene ID Symbol |
Klrb1c (Mouse) |
Gene ID Aliases | AI462337; CD161; Klrb1b; Ly-59; Ly55c; Ly59; NK-RP1; NK1.1; NKR-P1.9; NKRP1; NKRP140; Nk-1; Nk-1.2; Nk1; Nk1.2; Nkrp1b; Nkrp1c; ly-55c |
UniProt ID |
P27814 (Mouse |
UniProt Name |
KLRBC_MOUSE (Mouse) |
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