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Mouse Anti-Mouse I-Ad-UNLB (34-5-3)
Cat. No.:
1901-01
Purified Anti-Mouse I-Ad antibody for use in flow cytometry, immunoprecipitation, activation, blocking, and cytotoxicity assays.
$234.00
| Clone | 34-5-3 |
|---|---|
| Isotype | Mouse (C3H) IgG2aκ |
| Isotype Control | Mouse IgG2a-UNLB (HOPC-1) |
| Specificity | Mouse I-Ad |
| Alternative Names | MHC Class II, I-bd, I-Aβ, H2-I/Adβ |
| Description | The monoclonal antibody 34-5-3 reacts with the β chain of the I-Ad MHC class II alloantigen. It cross-reacts with I-Ab and with cells from mice of the H-2p and H-2q halotypes. |
| Immunogen | (C57BL/6 x DBA/2)F1 mouse splenocytes |
| Conjugate | UNLB (Unconjugated) |
| Buffer Formulation | Borate buffered saline, pH 8.2 |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C |
| Applications | Flow Cytometry – Quality tested 5 Immunoprecipitation – Reported in literature 2 Activation – Reported in literature 4 Blocking – Reported in literature 3 Cytoxicity – Reported in literature 1 |
| RRID Number | AB_2795478 |
| Gene ID | 14961 (Mouse) |
| Gene ID Symbol | H2-Ab1 (Mouse) |
| Gene ID Aliases | IAb; Ia2; Ia-2; Abeta; H-2Ab; H2-Ab; Rmcs1; I-Abeta; AI845868 |
| UniProt ID | P01921 (Mouse |
| UniProt Name | HB2D_MOUSE (Mouse) |
Documentation
Certificate of Analysis Lookup
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- 1. Ozato K, Mayer NM, Sachs DH. Monoclonal antibodies to mouse major histocompatibility complex antigens. IV. A series of hybridoma clones producing anti-H-2d antibodies and an examination of expression of H-2d antigens on the surface of these cells. Transplantation. 1982;34:113-9. (Immunogen, Cyto)
- 2. Bobé P, Benihoud K, Kiger N. Allogenic MHC class II determinant(s) in MRL-Ipr autoimmune disease-prone mice. Unusual expression of an L1 transposable element creates molecular mimicry. J Immunol. 1993;151:2813-9. (IP)
- 3. Mozes E, Dayan M, Zisman E, Brocke S, Licht A, Pecht I. Direct binding of a myasthenia gravis related epitope to MHC class II molecules on living murine antigen-presenting cells. EMBO J. 1989;8:4049-52. (Block)
- 4. Bishop GA, Frelinger JA. Haplotype-specific differences in signaling by transfected class II molecules to a Ly-1+ B-cell clone. Proc Natl Acad Sci USA. 1989;86:5933-7. (Activ)
- 5. Grusby MJ, Johnson RS, Papaioannou VE, Glimcher LH. Deletion of CD4+ T cells in major histocompatibility complex class II-deficient mice. Science. 1991;253:1417-20. (FC)
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