Sign in / Register 
Mouse Anti-Human IL-31-UNLB (SB118b)
Cat. No.:
15630-01
Purified Anti-Human IL-31 antibody for use in ELISA assays.
$198.00
| Clone | SB118b |
|---|---|
| Isotype | Mouse (BALB/c) IgG2bκ |
| Isotype Control | Mouse IgG2b-UNLB (A-1) |
| Specificity | Human IL-31 |
| Alternative Names | Interleukin-31 |
| Description | Interleukin-31 (IL-31) is a 24 kDa α-helical protein and a member of the IL-6 family of cytokines that is preferentially expressed by CD4+ T cells. This cytokine elicits its response by binding to a heterodimeric complex consisting of a gp130-like receptor chain and the oncostatin M receptor subunit. On target cells which include a broad range of immune and non-immune cells, IL-31 binding can induce activation of the Jak/STAT, AKT, and MAPK signaling pathways. Due to the ubiquitous expression of its receptor complex, IL-31 has numerous physiological roles that include regulating hematopoiesis and immune response. Over-expression has been linked to chronic inflammatory states such as dermatitis, pruritus, airway hypersensitivity, and inflammatory bowel disease. |
| Immunogen | E. coli-expressed human IL-31 |
| Conjugate | UNLB (Unconjugated) |
| Buffer Formulation | Borate buffered saline, pH 8.2 |
| Clonality | Monoclonal |
| Concentration | 1.0 mg/mL |
| Volume | 0.1 mL |
| Recommended Storage | 2-8°C |
| Applications | ELISA – Quality tested |
| RRID Number | AB_2794926 |
| Gene ID | 386653 (Human) |
| Gene ID Symbol | IL31 (Human) |
| Gene ID Aliases | IL-31 |
| UniProt ID | Q6EBC2 (Human |
| UniProt Name | IL31_HUMAN (Human) |
Documentation
Certificate of Analysis Lookup
Enter the Catalog Number and Lot Number for the Certificate of Analysis you wish to view
Related Products
Check items to add to the cart or
