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Mouse Anti-Human CD79b-APC (CB3-1)
Cat. No.:
9710-11
APC Anti-Human CD79b antibody for use in flow cytometry assays.
$286.00
| Clone | CB3-1 |
|---|---|
| Isotype | Mouse (BALB/c) IgG1κ |
| Isotype Control | Mouse IgG1-APC (15H6) |
| Specificity | Human CD79b |
| Alternative Names | B29, Igβ |
| Description | CD79 is a disulfide-linked heterodimer composed of an α chain (CD79a) and a β chain (CD79b) that associates non-covalently with membrane immunoglobulin to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage and remaining through all stages of B cell differentiation prior to plasma cells. Crosslinking of the BCR leads to B cell activation. The monoclonal antibody CB3-1 reacts with the β chain of CD79. |
| Immunogen | Ramos B cells |
| Conjugate | APC (Allophycocyanin) |
| Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
| Clonality | Monoclonal |
| Concentration | Lot specific |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C; Avoid exposure to light; Do not freeze |
| Applications | Flow Cytometry – Quality tested 1,3-5 Immunoprecipitation – Reported in literature 1,2 Western Blot – Reported in literature 1 |
| RRID Number | AB_2797071 |
| Gene ID | 974 (Human) |
| Gene ID Symbol | CD79B (Human) |
| Gene ID Aliases | AGM6; B29; IGB |
| UniProt ID | P40259 (Human |
| UniProt Name | CD79B_HUMAN (Human) |
Documentation
Certificate of Analysis Lookup
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- 1. Nakamura T, Kubagawa H, Cooper MD. Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies. Proc Natl Acad Sci USA. 1992;89:8522-6. (Immunogen, IP, WB, FC)
- 2. Lévéille C, Castaigne J, Charron D, Al-Daccak R. MHC class II isotype-specific signaling complex on human B cells. Eur J Immunol. 2002;32:2282-91. (IP)
- 3. Lanvin O, Guglielmi P, Fuentes V, Gouilleux-Gruart V, Mazière C, Bissac E, et al. TGF-β1 modulates Fas (APO-1/CD95)-mediated apoptosis of human pre-B cell lines. Eur J Immunol. 2003;33:1372-81. (FC)
- 4. Demurtas A, Stacchini A, Aliberti S, Chiusa L, Chiarle R, Novero D. Tissue flow cytometry immunophenotyping in the diagnosis and classification of non-Hodgkin's lymphomas: a retrospective evaluation of 1,792 cases. Cytometry B Clin Cytom. 2013;84B:82-95. (FC)
- 5. Stacchini A, Aliberti S, Pacchioni D, Demurtas A, Isolato G, Gazzera C, et al. Flow cytometry significantly improves the diagnostic value of fine needle aspiration cytology of lymphoproliferative lesions of salivary glands. Cytopathology. 2014;25:231-40. (FC)
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