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Clone | 143-30 |
---|---|
Isotype | Mouse IgG1κ |
Isotype Control | Mouse IgG1-UNLB (15H6) |
Specificity | Human CD55 |
Alternative Names | DAF, decay accelerating factor |
Description | CD55, also known as decay accelerating factor (DAF), is an 80 kDa GPI-anchored single chain glycoprotein that is expressed on all cells in contact with serum including all hematopoietic cells and the vascular endothelium. A soluble form of CD55 is present in plasma and body fluids. CD55 is a member of the regulator of complement activity (RCA) family of proteins and is thought to play a role in the protection of cells from damage by autologous complement by preventing the amplification steps of the complement cascade. CD55 expression increases upon T cell activation and antibodies to CD55 are mitogenic in the presence of phorbol esters. |
Immunogen | PHA activated peripheral blood mononuclear cells |
Conjugate | UNLB (Unconjugated) |
Buffer Formulation | Borate buffered saline, pH 8.2 |
Clonality | Monoclonal |
Concentration | 0.1 mg/mL |
Volume | 1.0 mL |
Recommended Storage | 2-8°C |
Applications |
Flow Cytometry – Quality tested 5,6 Immunohistochemistry-Frozen Sections – Reported in literature 1 Immunohistochemistry-Paraffin Sections – Reported in literature 2 Immunoprecipitation – Reported in literature 3 Western Blot-Non-Reducing – Reported in literature 4 |
RRID Number | AB_2797046 |
Gene ID |
1604 (Human) |
Gene ID Symbol |
CD55 (Human) |
Gene ID Aliases | CR; TC; DAF; CROM; CHAPLE |
UniProt ID |
P08174 (Human |
UniProt Name |
DAF_HUMAN (Human) |
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