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Mouse Anti-Human CD36-FITC (SMφ)
Cat. No.:
9605-02
FITC Anti-Human CD36 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blot assays.
$212.00
| Clone | SMφ |
|---|---|
| Isotype | Mouse (BALB/c) IgMκ |
| Isotype Control | Mouse IgM-FITC (11E10) |
| Specificity | Human CD36 |
| Alternative Names | GPIIIb, GPIV, OKM5-antigen, PASIV |
| Description | CD36, also known as GPIV, is an 88 kDa glycoprotein that is a receptor for extracellular matrix proteins such as collagen and thrombospondin. Its expression is restricted to platelets, monocytes, macrophages, erythrocyte precursors, adipocytes, activated keratinocytes, and some endothelial and epithelial cells. CD36 is a multifunctional protein that has roles as a cell adhesion molecule, a scavenger receptor, a signal transducer and in the pathogenesis of malaria via its affinity for Plasmodium falciparum erythrocyte membrane protein 1 (PEMP1). CD36 on macrophages functions in the phagocytic clearance of apoptotic cells. |
| Immunogen | Tonsil cells and peripheral blood mononuclear cells |
| Conjugate | FITC (Fluorescein) |
| Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide |
| Clonality | Monoclonal |
| Concentration | Lot specific |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C; Avoid exposure to light |
| Applications |
Flow Cytometry – Quality tested 1 Immunohistochemistry-Frozen Sections – Reported in literature 1 Immunohistochemistry-Paraffin Sections – Reported in literature 2 Immunocytochemistry – Reported in literature 1 Western Blot-Non-Reducing – Reported in literature 3,4 Blocking – Reported in literature 5 Separation – Reported in literature 6 ELISA – Reported in literature 7 |
| RRID Number | AB_2796999 |
| Gene ID |
948 (Human) |
| Gene ID Symbol |
CD36 (Human) |
| Gene ID Aliases | BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3 |
| UniProt ID |
P16671 (Human |
| UniProt Name |
CD36_HUMAN (Human) |
Documentation
Certificate of Analysis Lookup
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- 1. Hogg N, MacDonald S, Slusarenko M, Beverley PC. Monoclonal antibodies specific for human monocytes, granulocytes and endothelium. Immunology. 1984;53:753-67. (Immunogen, IHC-FS, ICC, FC)
- 2. Noguera A, Gomez C, Faner R, Cosio B, González-Périz A, Clà ria J, et al. An investigation of the resolution of inflammation (catabasis) in COPD. Respir Res. 2012;13:101. (IHC-PS)
- 3. Janciauskiene S, Wright HT, Lindgren S. Atherogenic properties of human monocytes induced by the carboxyl terminal proteolytic fragment of alpha-1-antitrypsin. Atherosclerosis. 1999;147:263-75. (WB)
- 4. Moraga F, Janciauskiene S. Activation of primary human monocytes by the oxidized form of α1-antitrypsin. J Biol Chem. 2000;275:7693-700. (WB)
- 5. Savill J, Hogg N, Ren Y, Hasiett C. Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. J Clin Invest. 1992;90:1513-22. (Block)
- 6. Lindsey JW, Hatfield LM. Epstein-Barr virus and multiple sclerosis: cellular immune response and cross-reactivity. J Neuroimmunol. 2010;229:238-42. (Sep)
- 7. Thibert M, Cristofari M, Romagné O, Legrand C. Charcterization of platelet panel CD36 mAb and a study of their effects on platelet activation. In: Schlossman SF, Boumsell L, Gilks W, Harlan JM, Kishimoto T, Morimoto C, et al, editors. Leukocyte Typing V: White Cell Differentiation Antigens. Oxford: Oxford University Press; 1995. p. 1274-8. (ELISA)
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