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Clone | 3G8 |
---|---|
Isotype | Mouse (CD2F1) IgG1κ |
Isotype Control | Mouse IgG1-PE (15H6) |
Specificity | Human/Chimpanzee CD16 |
Alternative Names | FcγRIII, low affinity Fc receptor |
Description | CD16, a member of the immunoglobulin superfamily, is a 50-65 kDa glycoprotein found as both a transmembrane and GPI-linked form. The transmembrane form of CD16 is expressed on NK cells, granulocytes, macrophages, and mast cells but not on eosinophils. The GPI-anchored type of CD16 is found only on neutrophils. CD16 is involved in NK activation and signal transduction. |
Immunogen | Human polymorphonuclear leukocytes |
Conjugate | PE (R-phycoerythrin) |
Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
Clonality | Monoclonal |
Concentration | Lot specific |
Volume | 1.0 mL |
Recommended Storage | 2-8°C; Avoid exposure to light; Do not freeze |
Applications |
Flow Cytometry – Quality tested 2,3,5-7 Immunohistochemistry-Frozen Sections – Reported in literature 4 Immunocytochemistry – Reported in literature 3 Immunoprecipitation – Reported in literature 1,2 Western Blot-Non-Reducing – Reported in literature 3 Stimulation – Reported in literature 5 Costimulation – Reported in literature 5 Blocking – Reported in literature 1 |
RRID Number | AB_2796964 |
Gene ID |
2214 (Human) 2215 (Human) 457457 (Chimpanzee) 745350 (Chimpanzee) |
Gene ID Symbol |
FCGR3A (Human) FCGR3B (Human) LOC457457 (Chimpanzee) LOC745350 (Chimpanzee) |
Gene ID Aliases | CD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20; CD16b; FCGR3A; FCRIIIb; CK820_G0056287; FCGR3B |
UniProt ID |
P08637 (Human O75015 (Human |
UniProt Name |
FCG3A_HUMAN (Human) FCG3B_HUMAN (Human) |
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