Mouse Anti-Cytokeratin 18-UNLB (SB38b)
Cat. No.:
10085-01
Purified Anti-Cytokeratin 18 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, ELISA, western blot assays.
$204.00
![Human pancreatic carcinoma cell line MIA PaCa-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Donkey Anti-Mouse IgG(H+L), Multi-Species SP ads-AF555 (SB Cat. No. 6415-32) and DAPI.](https://www.southernbiotech.com/media/catalog/product/cache/7215ceb8c027a94f96b2599083a59844/6/8/68bbae797bb10a0682f051f893a75e7577400aac7f832a02a18693c46bdb92a3.jpeg)
![Human pancreatic carcinoma cell line MIA PaCa-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Donkey Anti-Mouse IgG(H+L), Multi-Species SP ads-AF555 (SB Cat. No. 6415-32) and DAPI.](https://www.southernbiotech.com/media/catalog/product/cache/bea6149526ccf959e2544cf4e4180429/6/8/68bbae797bb10a0682f051f893a75e7577400aac7f832a02a18693c46bdb92a3.jpeg)
![Human epithelial carcinoma cell line HEp-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Goat Anti-Mouse IgG<sub>2b</sub>, Human/Bovine/Horse SP ads-FITC (SB Cat. No. 1093-02) and DAPI.](https://www.southernbiotech.com/media/catalog/product/cache/bea6149526ccf959e2544cf4e4180429/4/b/4b717745773c9a396b309f4ef230cbec23eafc0ec6eadd6758acac50822f9beb.jpeg)
Clone | SB38b |
---|---|
Isotype | Mouse (BALB/c) IgG2bκ |
Isotype Control | Mouse IgG2b-UNLB (A-1) |
Specificity | Cytokeratin 18 |
Alternative Names | CK 18, keratin 18 |
Description | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18 is a type I intermediate filament protein that exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia and is often co-expressed with cytokeratin 8. Tissues from the gastrointestinal tract, respiratory tract, and urogenital tract as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18. |
Immunogen | Recombinant N-terminal cytokeratin 18 |
Conjugate | UNLB (Unconjugated) |
Buffer Formulation | Borate buffered saline, pH 8.2 |
Clonality | Monoclonal |
Concentration | 0.1 mg/mL |
Volume | 1.0 mL |
Recommended Storage | 2-8°C |
Applications |
ELISA – Quality tested FLISA – Quality tested Immunohistochemistry-Paraffin Sections 1 Immunocytochemistry 1 Flow Cytometry 2 Western Blot 2 |
RRID Number | AB_2794113 |
Gene ID |
3875 (Human) |
Gene ID Symbol |
KRT18 (Human) |
Gene ID Aliases | CK-18; CYK18; K18 |
UniProt ID |
P05783 (Human |
UniProt Name |
K1C18_HUMAN (Human) |
Documentation
Certificate of Analysis Lookup
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- 1. SouthernBiotech published data (IHC-PS, ICC)
- 2. SouthernBiotech unpublished data (FC, WB)