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Hamster Anti-Mouse CD79b-LE/AF (HM79-12)
Cat. No.:
1830-14
Low Endotoxin/Azide Free Anti-Mouse CD79b antibody for use in flow cytometry, western blot, and immunoprecipitation assays.
$363.00
| Clone | HM79-12 |
|---|---|
| Isotype | Hamster (Armenian) IgG1 |
| Isotype Control | Hamster IgG-LE/AF |
| Specificity | Mouse CD79b |
| Alternative Names | B29, Igβ |
| Description | Murine CD79 is a disulfide-linked heterodimer composed of an α chain (CD79a) and a β chain (CD79b) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. |
| Immunogen | CD79α/CD79β heterodimers purified from mouse (BALB/c x NZB)F1 B cell lymphoma cells, WEHI231 |
| Conjugate | LE/AF (Low Endotoxin/Azide Free) |
| Buffer Formulation | Phosphate buffered saline, pH 7.4 |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C; Handle under aseptic conditions |
| Applications | Flow Cytometry – Quality tested 1-3 Immunoprecipitation – Reported in literature 1,2 Western Blot – Reported in literature 1 |
| RRID Number | AB_2795408 |
| Gene ID | 15985 (Mouse) |
| Gene ID Symbol | Cd79b (Mouse) |
| Gene ID Aliases | B29; Ig-beta; Igb; Igbeta |
| UniProt ID | P15530 (Mouse |
| UniProt Name | CD79B_MOUSE (Mouse) |
Documentation
Certificate of Analysis Lookup
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- 1. Koyama M, Ishihara K, Karasuyama H, Cordell JL, Iwamoto A, Nakamura T. CD79α/CD79β heterodimers are expressed on pro-B cell surfaces without associated μ heavy chain. Int Immunol. 1997;9:1767-72. (Immunogen, FC, IP, WB)
- 2. Kato I, Miyazaki T, Nakamura T, Kudo A. Inducible differentiation and apoptosis of the pre-B cell receptor-positive pre-B cell line. Int Immunol. 2000;12:325-34. (IP, FC)
- 3. McHeyzer-Williams LJ, Cool M, McHeyzer-Williams MG. Antigen-specific B cell memory: expression and replenishment of a novel b220(-) memory b cell compartment. J Exp Med. 2000;191:1149-65. (FC)
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