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  • Goat F(ab')2 Anti-Human IgD-AF647

Goat F(ab')2 Anti-Human IgD-AF647

Cat. No.:
2032-31
Goat F(ab')2 Anti-Human IgD-Alexa Fluor® 647 antibody for use in flow cytometry and immunohistochemistry assays.
$181.00
Size Price (USD) Quantity
0.5 mg $181.00
Technical Bulletin Safety Datasheet

Product Specifications

More Information
Isotype Goat F(ab')2 IgG
Isotype Control 0110-31
Specificity Reacts with the heavy chain of human IgD
Source Pepsin digest of Goat Anti-Human IgD (SB Cat. No. 2030)
Cross Adsorption Human IgG, IgM, and IgA; may react with IgD from other species
Conjugate AF647 (Alexa Fluor® 647)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide
Clonality Polyclonal
Concentration 0.5 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C; Avoid exposure to light
Trademark Information Alexa Fluor® is a registered trademark of Thermo Fisher Scientific, Inc. or its subsidiaries
Applications Quality tested applications for relevant formats include -
ELISA
FLISA
Flow Cytometry 3-5,7-11

Other referenced applications for relevant formats include -
Immunohistochemistry-Frozen Sections 1-3,6,9
Immunohistochemistry-Paraffin Sections 3
Separation 1,6
Stimulation 12-14
RRID Number AB_2795638
Gene ID 3495 (Human)
Gene ID Symbol IGHD (Human)
UniProt ID P01880 (Human
UniProt Name IGHD_HUMAN (Human)

Documentation

Documentation
Technical Bulletin Safety Datasheet
Certificate of Analysis Lookup

Enter the Catalog Number and Lot Number for the Certificate of Analysis you wish to view


Need help with this product?
Email technical support
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Other Conjugates and Formulations

Citations

  1. 1. Xu W, He B, Chiu A, Chadburn A, Shan M, Buldys M, et al. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI. Nat Immunol. 2007;8:294-303. (IHC-FS, Sep)
  2. 2. Xu W, Santini PA, Matthews AJ, Chiu A, Plebani A, He B, et al. Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF. J Immunol. 2008;181:276-87. (IHC-FS)
  3. 3. Chen K, Xu W, Wilson M, He B, Miller NW, Bengtén E, et al. Immunoglobulin D enhances immune surveillance by activating antimicrobial, pro-inflammatory and B cell-stimulating programs in basophils. Nat Immunol. 2009;10:889-98. (IHC-FS, IHC-PS, FC)
  4. 4. Green LL, Jakobovits A. Regulation of B cell development by variable gene complexity in mice reconstituted with human immunoglobulin yeast artificial chromosomes. J Exp Med. 1998;188:483-95. (FC)
  5. 5. Joseph AM, Babcock GJ, Thorley-Lawson DA. EBV persistence involves strict selection of latently infected B cells. J Immunol. 2000;165:2975-81. (FC)
  6. 6. He B, Xu W, Santini PA, Polydorides AD, Chiu A, Estrella J, et al. Intestinal bacteria trigger T cell-independent immunoglobulin A2 class switching by inducing epithelial-cell secretion of the cytokine APRIL. Immunity. 2007;26:812-26. (Sep, IHC-FS)
  7. 7. Warnatz K, Schlesier M. Flowcytometric phenotyping of common variable immunodeficiency. Cytometry B Clin Cytom. 2008;74:261-71. (FC)
  8. 8. He B, Santamaria R, Xu W, Cols M, Chen K, Puga I, et al. The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88. Nat Immunol. 2010;11:836-45. (FC)
  9. 9. Puga I, Cols M, Barra CM, He B, Cassis L, Gentile M, et al. B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen. Nat Immunol. 2012;13:170-80. (FC, IHC-FS)
  10. 10. Gieseke F, Mang P, Viebahn S, Sonntag I, Kruchen A, Erbacher A, et al. Siglec-7 tetramers characterize B-cell subpopulations and leukemic blasts. Eur J Immunol. 2012;42:2176-86. (FC)
  11. 11. Li FJ, Schreeder DM, Li R, Wu J, Davis RS. FCRL3 promotes TLR9-induced B-cell activation and suppresses plasma cell differentiation. Eur J Immunol. 2013;43:2980-92. (FC)
  12. 12. Jiang A, Clark EA. Involvement of Bik, a proapoptotic member of the Bcl-2 family, in surface IgM-mediated B cell apoptosis. J Immunol. 2001;166:6025-33. (Stim)
  13. 13. Rankin AL, Seth N, Keegan S, Andreyeva T, Cook TA, Edmonds J, et al. Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis. J Immunol. 2013;191:4540-50. (Stim)
  14. 14. Smith MJ, Packard TA, O'Neill SK, Dunand CJ, Huang M, Fitzgerald-Miller L, et al. Loss of anergic B cells in pre-diabetic and new onset T1D patients. Diabetes. 2014 Dec 18. pii: DB_131798. [Epub ahead of print]. (Stim)
See All References

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