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Mouse Anti-Human CD51 (Integrin αv)
ANTIGEN DESCRIPTION
CD51 represents the 150 kDa integrin αV chain that associates with integrin β3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils and platelets. CD51 is the most promiscuous integrin a subunit; it can form heterodimers with the β1 (CD29), β3 (CD61), β5, β6 and β8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins, including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.
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[Technical Bulletin / References ]
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Cat. No.
Product Description
Clone
Size
USD Price
Order Qty
9656-01
Mouse Anti-Human CD51-UNLB
13C2
0.1 mg
$98.00
9656-02
Mouse Anti-Human CD51-FITC
13C2
100 tests
$180.00
9656-09
Mouse Anti-Human CD51-R-PE
13C2
100 tests
$225.00
FORMAT ABBREVIATIONS:
UNLB
- purified, unlabeled antibody
FITC
- fluorescein isothiocyanate-labeled
TRITC
- tetramethlyrhodamine isothiocyanate
AP
- alkaline phosphatase-labeled
HRP
- horseradish peroxidase-labeled
BGAL
- B-galactosidase-labeled
TXRD
- Texas Red
TM
BIOT
- biotin-labeled
R-PE
- R-phycoerythrin-labeled
R-PE/TXRD
- R-phycoerythrin/Texas Red
TM
APC
- allophycocyanin
CY3
- Cyanine
TM
3-labeled *
SPRD
- SpectralRed
TM
-labeled *
LE/AF
- low endotoxin/azide-free
CY5
- Cyanine
TM
5-labeled *
R-PE/CY5.5
- R-phycoerythrin/Cyanine
TM
5.5-labeled *
R-PE/CY7
- R-phycoerythrin/Cyanine
TM
7-labeled *
APC/CY5.5
- allophycocyanin/Cyanine
TM
5.5-labeled *
APC/CY7
- allophycocyanin/Cyanine
TM
7-labeled *
FLMA
- fluorescein-5-malemide-labeled
SEPH
- sepharose-labeled
BIMA
- biotin-maleimide-labeled
NOTE:
*SpectralRed
TM
(SPRD) is a tandem conjugate of R-phycoerythrin and CY
TM
5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.
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