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Rat Anti-Mouse CD107a (LAMP-1)

ANTIGEN DESCRIPTION
CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles.[1] It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion.[2] CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice.[3] LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.[4]
[Technical Bulletin / References ] Back to CD Markers and Other Cell Surface Proteins Product List
 Cat. No.Product DescriptionCloneSize
USD Price
Order Qty
1920-01
 
Rat Anti-Mouse CD107a/LAMP-1-UNLB
1D4B 0.5 mg
$225.00
1920-02
 
Rat Anti-Mouse CD107a/LAMP-1-FITC
1D4B 0.5 mg
$275.00
1920-11
 
Rat Anti-Mouse CD107a/LAMP-1-APC
1D4B 0.1 mg
$192.00
1920-30
 
Rat Anti-Mouse CD107a/LAMP-1-Alexa Fluor 488
1D4B 0.1 mg
$190.00
FORMAT ABBREVIATIONS:
UNLB - purified, unlabeled antibody
FITC - fluorescein isothiocyanate-labeled
TRITC - tetramethlyrhodamine isothiocyanate
AP - alkaline phosphatase-labeled
HRP - horseradish peroxidase-labeled
BGAL - B-galactosidase-labeled
TXRD - Texas RedTM
BIOT - biotin-labeled
R-PE - R-phycoerythrin-labeled
R-PE/TXRD - R-phycoerythrin/Texas RedTM
APC - allophycocyanin
 CY3 - CyanineTM 3-labeled *
SPRD - SpectralRedTM-labeled *
LE/AF - low endotoxin/azide-free
CY5 - CyanineTM5-labeled *
R-PE/CY5.5 - R-phycoerythrin/CyanineTM5.5-labeled *
R-PE/CY7 - R-phycoerythrin/CyanineTM7-labeled *
APC/CY5.5 - allophycocyanin/CyanineTM5.5-labeled *
APC/CY7 - allophycocyanin/CyanineTM7-labeled *
FLMA - fluorescein-5-malemide-labeled
SEPH - sepharose-labeled
BIMA - biotin-maleimide-labeled
NOTE: *SpectralRedTM (SPRD) is a tandem conjugate of R-phycoerythrin and CYTM5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.