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Mouse anti-Human Interleukin-18 (IL-18)

DESCRIPTION
Interleukin-18 (IL-18), also known as IFNγ inducing factor, is an 18kD protein and a member of the IL-1 family. This pro-inflammatory cytokine is primarily produced by antigen-presenting cells including monocytes/macrophages, as well as in keratinocytes and mucosal cell populations. Upon binding to target cells, IL-18 can induce natural killer (NK) cell activity, proliferation of activated T lymphocytes and release of numerous pro-inflammatory cytokines[2,3]. Moreover, this cytokine can promote Fas Ligand expression in NK cells and enhance Fas Ligand-mediated cytotoxicity of Th1 cells[4]. Upregulation of IL-18 has been linked to several chronic inflammatory conditions including rheumatoid arthritis, heart disease and atherosclerosis[5-8].
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 Cat. No.Product DescriptionCloneSize
USD Price
Order Qty
15800-01
 
Mouse Anti-Human IL-18-UNLB
SB116C 0.5 mg
$225.00
15800-08
 
Mouse Anti-Human IL-18-BIOT
SB116C 0.5 mg
$330.00
FORMAT ABBREVIATIONS:
UNLB - purified, unlabeled antibody
FITC - fluorescein isothiocyanate-labeled
TRITC - tetramethlyrhodamine isothiocyanate
AP - alkaline phosphatase-labeled
HRP - horseradish peroxidase-labeled
BGAL - B-galactosidase-labeled
TXRD - Texas RedTM
BIOT - biotin-labeled
R-PE - R-phycoerythrin-labeled
R-PE/TXRD - R-phycoerythrin/Texas RedTM
APC - allophycocyanin
 CY3 - CyanineTM 3-labeled *
SPRD - SpectralRedTM-labeled *
LE/AF - low endotoxin/azide-free
CY5 - CyanineTM5-labeled *
R-PE/CY5.5 - R-phycoerythrin/CyanineTM5.5-labeled *
R-PE/CY7 - R-phycoerythrin/CyanineTM7-labeled *
APC/CY5.5 - allophycocyanin/CyanineTM5.5-labeled *
APC/CY7 - allophycocyanin/CyanineTM7-labeled *
FLMA - fluorescein-5-malemide-labeled
SEPH - sepharose-labeled
BIMA - biotin-maleimide-labeled
NOTE: *SpectralRedTM (SPRD) is a tandem conjugate of R-phycoerythrin and CYTM5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.